Purpose
Neuropathic pain can be life altering and difficult to treat. Nerves can be compressed
along their path in the upper extremities, resulting in chronic neuropathic pain.
This study was performed to evaluate the effectiveness and safety of multiple concomitant
distal nerve decompressions for the treatment of upper extremity nerve pain.
Methods
A retrospective review of patients from a single surgeon’s academic practice was performed
to identify those undergoing nerve decompressions for an indication of “pain” as the
referring diagnosis between April 2020 and June 2021. The primary outcomes included
patient-reported severity of pain using the Visual Analog Scale and quality-of-life
measures, including level of frustration, depression, and impact on quality of life
attributable to pain on a similar 0–10 Likert scale. Complications, if any, were also
determined.
Results
Eleven patients were identified to have undergone multiple concurrent nerve decompressions
for the indication of upper extremity pain. All sites chosen for decompression were
found to be provocative, ie, elicited increased pain on examination with compression.
The median number of decompressions performed was 5 (interquartile range, 4–6), ranging
from 3 to 7. The mean follow-up time was 5 months (SD, 3.43 months). The average pain
over the last month and the average pain over the past week had significant improvement
at the final follow-up, and there was a statistically significant decrease in the
patient-reported mean impact of pain on quality of life following decompressions (preoperative,
5.8; postoperative, 3.6; P = .017; 95% confidence interval, 0.2–4.3). No complications were identified.
Conclusions
Performing multiple concomitant nerve decompressions of the upper extremities is safe
and effective in the treatment of chronic neuropathic pain following upper extremity
trauma.
Type of study/level of evidence
Therapeutic IV.
Key words
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References
- Neuropathic pain in patients with upper-extremity nerve injury.Physiother Can. 2010; 62: 190-201
- The impact of neuropathic pain on health-related quality of life: review and implications.Neurology. 2007; 68: 1178-1182
- Biomedical and psychosocial factors associated with disability after peripheral nerve injury.J Bone Joint Surg Am. 2011; 93: 929-936
- Distal peroneal nerve decompression after sciatic nerve injury secondary to total hip arthroplasty.J Neurosurg. 2018; 130: 179-183
- Upper and lower extremity nerve injuries in pediatric missile wounds: a selective approach to management.Pediatr Surg Int. 2011; 27: 635-641
- Post-traumatic distal nerve entrapment syndrome.J Reconstr Microsurg. 1999; 15: 159-170
- Quadrilateral space syndrome: a review.J Shoulder Elbow Surg. 2018; 27: 950-956
- Chronic nerve compression--an experimental model in the rat.Ann Plast Surg. 1984; 13: 112-120
- Clinical commentary: pathogenesis of cumulative trauma disorder.J Hand Surg Am. 1994; 19: 873-883
- Multilevel nerve compression and muscle imbalance in work-related neuromuscular disorders.Am J Ind Med. 2002; 41: 343-352
- Peripheral nerve size in normals and patients with polyneuropathy: an ultrasound study.Muscle Nerve. 2009; 40: 960-966
- The significance of longitudinal excursion in peripheral nerves.Hand Clin. 1986; 2: 761-766
- Sensory nerve conduction velocity predicts improvement of hand function with nerve gliding exercise following carpal tunnel release surgery.J Clin Med. 2021; 10: 4121
- Nerve and tendon gliding exercises and the conservative management of carpal tunnel syndrome.J Hand Ther. 1998; 11: 171-179
- Longitudinal excursion and strain in the median nerve during novel nerve gliding exercises for carpal tunnel syndrome.J Orthop Res. 2007; 25: 972-980
Article info
Publication history
Published online: November 18, 2022
Accepted:
August 31,
2022
Received:
February 1,
2022
Footnotes
Declaration of interests: No benefits in any form have been received or will be received related directly or indirectly to the subject of this article.
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© 2022 THE AUTHORS. Published by Elsevier Inc. on behalf of The American Society for Surgery of the Hand.
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